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  • In Vitro Tests - Projects
    types of cancer NANOTHER Development and evaluation of nanoparticle toxicity and effectiveness in diagnosis and therapy using cell cultures 2008 2012 6FP European Project Subject nanoparticle toxicology Leader GAIKER IK4 Development of an in vitro model of the haematoencephalic barrier SYNTHEBAR Development and evaluation of a cell model useful for the evaluation of absorption in the haematoencephalic barrier 2010 2012 EMAITEK Project Funded by the Basque Government Subject cell model development Leader GAIKER IK4 Novel appraches for the development of automized skin treatments and services Test case dead sea minerals and conventional drugs SKINTREAT Evaluation of nanoparticle suitability for psoriasis treatment using skin cell cultures 2008 2012 7FP European Project Subject nanoparticle toxicology on skin Leader Ahava Dead Sea Laboratories Israel Evaluation of in vitro biological activity of vegetable extracts for use in cosmetic formulations Search using in vitro systems of beneficial activities to encourage the use of vegetable extracts in cosmetics 2009 2010 Private funding from client Subject cosmetics effectiveness Study of microsomal metabolic stability of drugs Evaluation of drug metabolic properties in CYP450 2009 2010 Private funding from client Subject pharmacokinetics and drug toxicity Characterisation of hepatoprotective activity during canned vegetable manufacturing Definition of liver protective effects during

    Original URL path: http://www.gaiker.es/ing/in_vitro_proyectos.aspx (2016-02-15)
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  • In Vitro Tests - Scientific Publications
    micro and nanoscale by thermal nanoimprint lithography on a new functionalized copolymer Journal of Vacuum Science and Technology B 27 6 2008 L Conte R de monserrat N Serra J R Montserrat A Alejandro Ensayo clínico de eficacia y tolerancia y estudio in vitro de la capacidad protectora e hidratante de un gel intranasal Acta otorrinolaringológica española 2 1 2 9 Posters 2007 L Conte R de Monserrat N Serra

    Original URL path: http://www.gaiker.es/ing/in_vitro_publicaciones.aspx (2016-02-15)
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  • Genomics
    in projects dealing with Functional genomics within knowledge areas such as toxicogenomics pharmacogenomics metagenomics or epigenetics among others By means of our RDN DNA microarray key tools we basically undertake studies on differential gene expression Moreover we are developing applications in DNA methylation technology study of gene expression regulation in genetic disorders and certain types of cancer miRNA study of gene expression regulation molecules as diagnostic markers and for the development of new therapies aCGH technology enabling the detection of changes in the number of DNA copies along the whole genome and quite useful in the identification of chromosome abnormalities etc Our Genomics lab is basically but not exclusively supported by the agilent technologies platform We make use of the following techniques among others Isolation of mRNA and total RNA samples from tissues and cell cultures RNA quality control using the bioanalyzer optimisation of amplification reactions and labelling with fluorophores one colour and two colour hybridisation on DNA microarrays data analysis and treatment using agilent genespring and Ingenuity pathway software etc Analysis of differential gene expression Hybridisation experimental of one colour and two colour hybridisation techniques Hybridisation on Agilent Platform microarrays Biostatistical analysis of data Functional analysis of results canonical

    Original URL path: http://www.gaiker.es/ing/genomica.aspx (2016-02-15)
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  • Genomics - Projects
    the presence of new phosphorylated early toxicology markers in a new immortal human hepatocyte cell line to be used in pharmacological tests 2009 2011 ETORTEK Project Funded by the Basque Government Subject Toxicogenomics Leader CIC BioGUNE Toxicogenomics and Toxicoproteomics of RNAi SIRNATOX Study of SiRNA toxicity based on the detection of new liver toxicity markers 2009 2010 ETORTEK Project Funded by the Basque Government Subject Toxicogenomics Leader CIC BioGUNE Development of a RNA microarray to diagnose pollution impact on soil s health LURCHIP Design of a low density RNA microarray as a fast and simple tool for the diagnosis of soil s health 2009 2010 Project for a Comprehensive Plan for Business Innovation Funded by the Biscay Provincial Council Subject Environmental Genomics Leader Neiker Creation and screening of a cDNA library from natural samples KERATO LIBRERÍA Isolation of a protease from long feathers for further industrial use 2009 2010 Private funding from client Subject Molecular Biology Improvement of the translational prediction of non clinical assays in humans MELIUS To provide a large amount of data from omic technologies to enable a thorough understanding of drug derived metabolic and cell mechanisms 2008 2010 CENIT Project Funded by the CDTI Spanish Centre

    Original URL path: http://www.gaiker.es/ing/genomica_proyectos.aspx (2016-02-15)
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  • Genomics - Scientific Publications
    cells Molecular Cancer Therapy Nov 6 11 2921 2927 Posters 2007 A García A Freije R Armañanzas I Inza Z Ispizua P Heredia P Larrañaga G López Vivanco T Suárez M Betanzos Gene expression model for the classification of human colorectal cancer and potential CRC biomarkers search Drug Discovery Technology poster session London UK 2006 A García A Freije R Armañanzas I Inza Z Ispizua P Heredia P Larrañaga G

    Original URL path: http://www.gaiker.es/ing/genomica_publicaciones.aspx (2016-02-15)
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  • Environmental Management - Projects
    IBERDROLA Engineering and Construction focusses on evaluating the sustainability of the different alternatives considered from environmental and social points of view 2010 2013 CENIT Project Backed by the Ministry of Economy and Competitiveness and funded by the Centre for the Development of Industrial Technology CDTI Subjects Algae energy environmental management life cycle analysis Leader Iberdrola Engineering and Construction Ecosustainability of ionic liquids for industrial applications LIQUION Research and generation of knowledge in ionic liquids and their application technologies by means of more environment friendly processes than those presently used with a view to meeting transport energy environment and biomedicine sector demands GAIKER s part in the project focusses on the sustainability of ionic liquids and of new products and processes developed under the project that include the use of ionic liquids GAIKER will also analyse possible ways of processing ionic liquids at the end of their life cycle 2010 2013 CENIT Programme Funded by the Ministry of Science and Innovation Subjects Life cycle analysis Environmental management Leader MAIER Ecodesign ecoinnovation and RFID identification technology for managing waste electrical and electronic equipment IDECO Optimisation and improvement of the current model of managing reusing and recycling Waste Electrical and Electronic Equipment WEEE by developing a global ITC management system to improve available information on waste and its traceability also the launch of an ecodesign platform to provide all necessary resources for its introduction to the design of new more sustainable and recyclable products 2010 2013 ETORGAI Project Funded by the Basque Government Subjects Waste recycling ecodesign Leader Inkoa Sistemas S L Strategic commerce research programme MERKABILA MERKABILA s aim is to better understand and advance in the development of strategic research in the field of Commerce Science through the convergence of traditional science and technology fields in order to increase competitiveness and

    Original URL path: http://www.gaiker.es/ing/gestion_proyectos.aspx (2016-02-15)
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  • Environmental Management - Scientific Publications
    Ecodiseño en el Sector Marítimo Bilbao 2011 L Barruetabeña El análisis de ciclo de vida como herramienta de gestión 17 Semana Europea de la Calidad Herramientas Metodológicas de Gestión Ambiental Zamudio 2011 L Barruetabeña Environmental aspects of OLEDS 23RD Working group meeting of the OE A Stuttgart Alemania 2011 L Barruetabeña Environmental impact for manufacture and recyclability Workshop on Processing for Flexible Polymer Electronic Devices Make it by the Mile

    Original URL path: http://www.gaiker.es/ing/gestion_publicaciones.aspx (2016-02-15)
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  • Thermoplastics - Projects
    Funded by the Basque Government Subject natural composites Leader MAIER S Coop Smart and adaptive side protection technologies ADAPTA Despite the high mortality rate for side on accidents there is currently no significant research into technologies concerning pre crash detection and protection The ADAPTA project involves research into comprehensive and adaptable lateral protection systems with the aim of reducing the number of victims and seriousness of side on crashes 2008 2011 CENIT Project Funded by the CDTI Spanish Centre for Industrial Technological Development Spanish Ministry of Science and Innovation Subject automotive Leader TRW Automotive S A Development and processing of natural polymer based bioplastics and or additives obtained from natural sources NATURPLASTIC The NATURPLASTIC project involves the study of the technical scope of new plastic materials from renewable biological sources as replacements for traditional materials but with a specific industrial outlook The project contemplates the use of bioplastics packaging and thermoplastic biocomposites automotive of natural polyols to produce foams construction and new functional natural bioadditives 2009 2010 EMAITEK Project Funded by the Basque Government Subject plastics from renewable sources Leader GAIKER IK4 The contribution of New Technologies to the development of future foodstuffs also known as future foodstuffs safer more nutritional more convenient and smarter FUTURAL FUTURAL is structured into six areas of activity each of which covers a new technology by way of a set of scientific objectives based on the foodstuff matrices most suitable for their incorporation Activity 5 which is headed by GAIKER IK4 and in which seven leading companies in their subsector participate aims to incorporate active agents into packaging film to prevent food degradation by inhibiting bacterial growth and a deterioration in safety due to the proliferation of food borne pathogens 2007 2010 CENIT Project Funded by the CDTI Spanish Centre for Industrial Technological Development

    Original URL path: http://www.gaiker.es/ing/materiales_termoplasticas_proyectos.aspx (2016-02-15)
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