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  • Tarifas - iib.uam.es
    News RSS feed aggregators Intranet Internal Tools Internal Information iib uam es Microscopy Specific Information Tarifas Presentation Functions Staff Contact Specific Information Regulations Manuales Tarifas Reactivos Programas Artìculos Prices Here you can check the current rates of service Prices Navigation Presentation Welcome Location History Biography of Alberto Sols Organization Organization chart Management Administration Institute Board Faculty Board Committees Commissions Research Research Groups Research Departments Scientific Reports Publications Services Administration and

    Original URL path: https://www.iib.uam.es/portal/en/web/microscopia/tarifas (2015-08-08)
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  • reactivos - iib.uam.es
    Functions Staff Contact Specific Information Regulations Manuales Tarifas Reactivos Programas Artìculos Reactivos En el servicio se distribuyen alícuotas de anticuerpos secundarios y otros reactivos indicados para microscopía Estos son los reactivos disponibles REACTIVOS En el servicio de microscopia también tenemos a disposición de los usuarios placas de IBIDI para la realización de experimentos in vivo En los siguientes links podéis ver las características Placas p35 pared alta IBITREAT Placas p35 pared baja IBITREAT Micro slides 8 wells IBITREAT actualmente están disponibles en el almacén Si necesitáis otro tipo de placas preguntarnos porque tenemos algunas de muestra Otros servicios cercanos que ofrecen alícuotas de productos que podeis necesitar son El servicio de microsopía confocal del Servicio Interdepartamental de Investigación SIdI de la Universidad Autónoma de Madrid Está situado en la facultad de medicina El servicio de microscopía óptica y confocal del Centro de Biología Molecular Severo Ochoa En la acutalidad no venden alicuotas a personal externo al CBM A continuación os dejamos los enlaces a casas comerciales con informacion sobre reactivos Jackson Immunoresearch información sobre la correcta elección de anticuerpos secundarios Molecular Probes Handbook IHC World Navigation Presentation Welcome Location History Biography of Alberto Sols Organization Organization chart Management Administration Institute

    Original URL path: https://www.iib.uam.es/portal/en/web/microscopia/reactivos (2015-08-08)
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  • Programas - iib.uam.es
    personal del servicio de informática nosotros solamente os proporcionamos la información sobre donde obtenerlo El programa de Zeiss para visualizar las imágenes del confocal LSM710 lo podeis obtener en este link Zen Zeiss El programa libre para la visualización modificación y edición de los videos realizados en el Cell Observer lo podeis descargar en este link Axiovision ImageJ Este software de análisis de imágen es libre y tiene infinitas posibilidades Se pueden realizar análisis de colocalización contajes de partículas medidas de intesidad de fluorescencia medición de áreas Para descargároslo teneis aqui el link Descarga de ImageJ Si necesitais ayuda para el manejo o el análisis de las imágenes poneros en contacto con nosotros Aqui teneis información que os puede resultar interesante Tutorial para iniciarse en el uso del Image J Manual general de Image J Basic Image Analysis and Manipulation in ImageJ Fiji Fiji is just ImageJ Este software es el mismo que el ImageJ pero tiene incluídos muchos plugins interesantes y se acutaliza frecuentemente Os lo recomendamos Para descargároslo aqui teneis el link FIJI En esta dirección podeis encotrar múltiples tutoriales que os pueden ayudar en vuestros análisis Tutoriales FIJI Otra versión de ImageJ que inlcuye diversos plugins WCIF ImageJ Tanto para el ImageJ como para el Fiji existen multiples plugins que os pueden ser de utilidad Algunos de los más usados os los ponemos a continuación Para análisis de colocalización os recomendamos el JACOP y el ICA Aunque existen mucho más Si estais interesados en analizar el movimento individual de partículas o células de manera manual os aconsejamos que os descargueis el pluging MANUAL TRACKING para el ImageJ Fiji Es muy sencillo de usar aqui os dejamos las instrucciones Si además quereis realizar gráficas para representar los datos obtenidos anteriormente podeis usar el programa Chemotaxis and migration tool

    Original URL path: https://www.iib.uam.es/portal/en/web/microscopia/programas (2015-08-08)
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  • Artìculos - iib.uam.es
    Directory Activities Calendar Scientific Events News RSS feed aggregators Intranet Internal Tools Internal Information iib uam es Microscopy Specific Information Artìculos Presentation Functions Staff Contact Specific Information Regulations Manuales Tarifas Reactivos Programas Artìculos Documentacion y artículos A continuacion encontrareis enlaces relacionados con la microscopia que pueden ser de vuestro interés La red española de microscopia óptica avanzada REMOA tiene una web en la que podeis encontrar información sobre otros servicios de microscopia cursos y equipamiento Página con informacion sobre todas las áreas de la microscopía microscopy primer Presentaciones sencillas sobre temas de microscopia presentations Para los que esteis interesados en métodos para clarear muestras aqui hay un resumen de los métodos más usados Clearing Methods En aquellos casos en los que tengais que hacer una inmunofluorescencia con dos enticuerpos de la misma especie podeis consultar la informacion de Jackson ImmunoResearch que os puede ser muy útil Artículos sobre análisis de colocalizacion Quantitative Colocalization Analysis of Fluorescence Microscopy Images Seminario del CBMSO muy detallado Navigation Presentation Welcome Location History Biography of Alberto Sols Organization Organization chart Management Administration Institute Board Faculty Board Committees Commissions Research Research Groups Research Departments Scientific Reports Publications Services Administration and Accounting Warehouse Digital Library Quality Control

    Original URL path: https://www.iib.uam.es/portal/en/web/microscopia/articulos (2015-08-08)
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  • Directory - iib.uam.es
    RSS feed aggregators Intranet Internal Tools Internal Information iib uam es Directory Directory IIBM Directory Service Name or Surname To find someone at the Biomedical Research Institute type at least two characters of the name or surname and click Search Navigation Presentation Welcome Location History Biography of Alberto Sols Organization Organization chart Management Administration Institute Board Faculty Board Committees Commissions Research Research Groups Research Departments Scientific Reports Publications Services Administration

    Original URL path: https://www.iib.uam.es/portal/en/personal?p_p_id=APPERSportlet_WAR_APIIBportlet_INSTANCE_vAb1&p_p_lifecycle=0&p_p_state=normal&p_p_mode=view&p_p_col_id=column-3&p_p_col_count=1&_APPERSportlet_WAR_APIIBportlet_INSTANCE_vAb1_action=search (2015-08-08)
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  • New therapeutic target for Parkinson's disease - News - iib.uam.es
    Biomedical Research on Neurodegenerative Diseases CIBERNED and CSIC UAM has validated inhibition of protein phosphodiesterase 7 PDE7 as a future therapeutic target for Parkinson s disease confirming its beneficial effects in cellular and animal models of this disorder In fact the group which had previously showed in 2011 that pharmacological inhibition of this protein had a potent neuroprotective and anti inflammatory effect has just published in the journal Stem Cells Translational Medicine its latest study on this line which shows that PDE7 inhibition also promotes the formation of new dopaminergic neurons The results obtained both in vitro and in animal models of Parkinson Disease indicate that this inhibition may regulate endogenous neurogenesis process thus promoting the formation of new dopaminergic neurons and contributing to the neurological tissue repair affected as a result of the development of the disease Thus it is demonstrated that inhibition of PDE7 not only has a potent neuroprotective and anti inflammatory effect but it may also be an effective method to replace the loss of dopaminergic neurons in Parkinson s patients The study was led by Jose Angel Morales García CIBERNED under supervision of Professor Ana Pérez Castillo at The Institute of Biomedical Research Alberto Sols

    Original URL path: https://www.iib.uam.es/portal/en/noticias/-/asset_publisher/p8JD/content/nueva-diana-terapeutica-en-la-enfermedad-del-parkinson?redirect=https%3A%2F%2Fwww.iib.uam.es%2Fportal%2Fen%2Fnoticias%3Fp_p_id%3D101_INSTANCE_p8JD%26p_p_lifecycle%3D0%26p_p_state%3Dnormal%26p_p_mode%3Dview%26p_p_col_id%3Dcolumn-3%26p_p_col_count%3D1 (2015-08-08)
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  • C-Raf deficiency leads to hearing loss and increased noise susceptibility. - News - iib.uam.es
    Activities News Calendar Scientific Events News RSS feed aggregators News Back C Raf deficiency leads to hearing loss and increased noise susceptibility The Neurobiology of Hearing group headed by Dr Isabel Varela Nieto in collaboration with Dr Ulf Rapp from the University of Wurzburg has published an study which describes the auditory phenotype of C Raf knock out mice C RAF is a kinases that modulate neurogenesis and neuritogenesis during inner ear development C RAF deficiency in humans is associated with deafness in rare genetic diseases In this study we show that the homozygous C Raf deletion in mice caused profound deafness with a remarkable reduction of the K channel Kir4 1 expression a trait that suffices as a cause of deafness In addition heterozygous C Raf mice showed higher sensibility to noise induced hearing loss through mechanisms involving the activation of JNK and an exacerbated apoptotic response These results have been published in the journal Cellular and Molecular Life Science de Iriarte Rodríguez R Magariños M Pfeiffer V Rapp UR Varela Nieto I C Raf deficiency leads to hearing loss and increased noise susceptibility Cell Mol Life Sci 2015 May 15 Navigation Presentation Welcome Location History Biography of Alberto

    Original URL path: https://www.iib.uam.es/portal/en/noticias/-/asset_publisher/p8JD/content/la-deficiencia-en-c-raf-produce-perdida-auditiva-y-una-mayor-sensibilidad-a-la-hipoacusia-inducida-por-exposicion-a-ruido?redirect=https%3A%2F%2Fwww.iib.uam.es%2Fportal%2Fen%2Fnoticias%3Fp_p_id%3D101_INSTANCE_p8JD%26p_p_lifecycle%3D0%26p_p_state%3Dnormal%26p_p_mode%3Dview%26p_p_col_id%3Dcolumn-3%26p_p_col_count%3D1 (2015-08-08)
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  • IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei. - News - iib.uam.es
    SIME Microscopy Directory Activities Calendar Scientific Events News RSS feed aggregators Intranet Internal Tools Internal Information iib uam es Activities News Calendar Scientific Events News RSS feed aggregators News Back IGF 1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei The Brain Structure and Function journal publishes a paper codirected by Drs Isabel Varela Nieto and Dr Jose Manuel Juiz Castilla la Mancha University that deeps into the morphologic and physiologic alterations of the cochlear nucleus the first step in the central auditive pathway in mice with Insulin like growth factor 1 IGF 1 deficiency This study confirms that Igf1 knockout mice present changes in the cochlear nucleus cytoarchitecture as well as in the expression of VGluT1 and VGAT transporters and MEF2 transcription factor Fuentes Santamaría V Alvarado JC Rodríguez de la Rosa L Murillo Cuesta S Contreras J Juiz JM Varela Nieto I IGF 1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei Brain Struct Funct 2014 Nov 7 Navigation Presentation Welcome Location History Biography of Alberto Sols Organization Organization chart Management Administration Institute Board

    Original URL path: https://www.iib.uam.es/portal/en/noticias/-/asset_publisher/p8JD/content/la-deficiencia-en-igf1-produce-atrofia-y-cambios-en-la-expresion-genica-de-los-factores-de-transcripcion-vglut1-y-mef2-en-el-nucleo-coclear-en-ratones?redirect=https%3A%2F%2Fwww.iib.uam.es%2Fportal%2Fen%2Fnoticias%3Fp_p_id%3D101_INSTANCE_p8JD%26p_p_lifecycle%3D0%26p_p_state%3Dnormal%26p_p_mode%3Dview%26p_p_col_id%3Dcolumn-3%26p_p_col_count%3D1 (2015-08-08)
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