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  • Research Groups - iib.uam.es
    Departments Cancer Biology Department Department of Endocrine and Nervous System Pathophysiology Department of Metabolism and Cell Signaling Department of Experimental Models of Human Disease Scientific Reports Scientific Reports in pdf format Publications Bioinformatics Additional Information Department the Laboratory belongs to Department of Cancer Biology Scientific Reports available Scientific Reports 2011 2012 Introduction Staff Research topics Publications Additional Information Navigation Presentation Welcome Location History Biography of Alberto Sols Organization Organization chart

    Original URL path: https://www.iib.uam.es/portal/en/investigacion/grupos?p_p_id=APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq&p_p_lifecycle=0&p_p_state=normal&p_p_mode=view&p_p_col_id=column-3&p_p_col_count=1&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_action=detail&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_id=1000&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_idJefe=3009&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_menu=info (2015-08-08)
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  • Directory - iib.uam.es
    es Directory Directory IIBM Directory Service Varela Nieto Isabel Category Profesor Investigación Position Responsable Cientifico ENNI Laboratory Neurobiology of Hearing 2 11 Department Department of Pathophysiology Endocrine and Nervous System Phone Number 34 91 585 4422 Fax 34 91 585 4401 E Mail ivarela Publications View publications New Search Back Navigation Presentation Welcome Location History Biography of Alberto Sols Organization Organization chart Management Administration Institute Board Faculty Board Committees Commissions

    Original URL path: https://www.iib.uam.es/portal/en/personal?p_p_id=APPERSportlet_WAR_APIIBportlet_INSTANCE_vAb1&p_p_lifecycle=0&p_p_col_id=column-3&p_p_col_count=1&_APPERSportlet_WAR_APIIBportlet_INSTANCE_vAb1_idPersona=258&_APPERSportlet_WAR_APIIBportlet_INSTANCE_vAb1_action=detail_person (2015-08-08)
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  • Research Groups - iib.uam.es
    and Drawing Facility Sterilization and Culture Media Preparation Radiation Protection Genomics MRISS IT Services SIME Microscopy Directory Activities Calendar Scientific Events News RSS feed aggregators Intranet Internal Tools Internal Information iib uam es Research Research Groups Research Groups Research Departments Cancer Biology Department Department of Endocrine and Nervous System Pathophysiology Department of Metabolism and Cell Signaling Department of Experimental Models of Human Disease Scientific Reports Scientific Reports in pdf format Publications Neurobiology of Hearing Staff Head of Group Varela Nieto Isabel Investigador Contratado Celaya Puértolas Adelaida Cervantes Sánchez Blanca Aurora Vallecillo Hernández Néstor Estancia Formación Checa Delage Isabel De Iriarte Rodríguez Rocío Molta Marc Pulido Sánchez Sara Estudiante García Mato Ángela Asesor Colaborador Baeza Ochoa de Ocáriz María Luisa Cediel Algovia Rafael Contreras Rodríguez Julio García Alcántara Fernando Lassaletta Atienza Luis Magariños Sánchez Marta Rivera Rodríguez Teresa Jesús Zubeldia Ortuño José Manuel Introduction Staff Research topics Publications Additional Information Navigation Presentation Welcome Location History Biography of Alberto Sols Organization Organization chart Management Administration Institute Board Faculty Board Committees Commissions Research Research Groups Research Departments Scientific Reports Publications Services Administration and Accounting Warehouse Digital Library Quality Control Labware Washing Facility Technical Support Biological Safety Comparative Medicine Cell Cultures Non Invasive Neurofunctional

    Original URL path: https://www.iib.uam.es/portal/en/investigacion/grupos?p_p_id=APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq&p_p_lifecycle=0&p_p_state=normal&p_p_mode=view&p_p_col_id=column-3&p_p_col_count=1&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_action=detail&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_id=23&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_idJefe=258&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_menu=miembros (2015-08-08)
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  • Research Groups - iib.uam.es
    is a rare disease associated with syndromic hearing loss and poor growth rates Human IGF I deficiency is a rare disease associated with syndromic hearing loss poor growth rates and mental retardation ORPHA73272 OMIM608747 Similarly Igf1 mice are dwarfs with low survival rates and congenital profound deafness which among other sensorial alterations develop retinal degeneration with ageing IGF I is known to be a neuroprotective agent accordingly the physiological age related decrease in circulating IGF I levels has been related to cognitive and brain alterations but there are no in depth studies addressing the relationship between IGF I levels and presbycusis There is also little information on the potential protective actions of IGF I in noise induced hearing loss Publications http www ncbi nlm nih gov pubmed term varela nieto 20i IGF I intracellular targets and sensorineural deafness Evaluation of new drug candidates for prevention and or treatment of sensorineural hearing loss Our objectives are to increase knowledge of the fine mechanism involved in the different causes of otic damage relevant of the human diseases in order to optimize conditions for evaluation of new drug candidates for prevention and or treatment of sensorineural hearing loss These results will help design of studies in animals as well as in human and may be a new standard for evaluation of new drug candidates This will include To establish of a well defined panel of stress and inflammatory markers of otic damage caused by noise low IGF I levels and their interaction To study the mechanisms of action of novel medicines in vivo and their potential for protection and or repair of hearing loss caused by excessive exposure to noise To develop in vivo studies in optimized conditions to evaluate the potency of novel medicines as a new tool for prevention treatment of

    Original URL path: https://www.iib.uam.es/portal/en/investigacion/grupos?p_p_id=APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq&p_p_lifecycle=0&p_p_state=normal&p_p_mode=view&p_p_col_id=column-3&p_p_col_count=1&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_action=detail&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_id=23&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_idJefe=258&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_menu=lineas (2015-08-08)
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  • Research Groups - iib.uam.es
    and Nervous System Pathophysiology Department of Metabolism and Cell Signaling Department of Experimental Models of Human Disease Scientific Reports Scientific Reports in pdf format Publications Neurobiology of Hearing Publications Scientific Report 2011 2012 Scientific Report 2006 2007 Scientific Report 2004 2005 Scientific Report 2002 2003 Scientific Report 2000 2001 All publications of the principal investigator View publications Back Introduction Staff Research topics Publications Additional Information Navigation Presentation Welcome Location History

    Original URL path: https://www.iib.uam.es/portal/en/investigacion/grupos?p_p_id=APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq&p_p_lifecycle=0&p_p_state=normal&p_p_mode=view&p_p_col_id=column-3&p_p_col_count=1&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_action=detail&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_id=23&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_idJefe=258&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_menu=public (2015-08-08)
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  • Research Groups - iib.uam.es
    Metabolism and Cell Signaling Department of Experimental Models of Human Disease Scientific Reports Scientific Reports in pdf format Publications Neurobiology of Hearing Additional Information Department the Laboratory belongs to Department of Pathophysiology Endocrine and Nervous System Scientific Reports available Scientific Reports 2011 2012 Scientific Reports 2008 2010 Scientific Reports 2006 2007 Scientific Reports 2004 2005 Scientific Reports 2002 2003 Scientific Reports 2000 2001 Introduction Staff Research topics Publications Additional Information

    Original URL path: https://www.iib.uam.es/portal/en/investigacion/grupos?p_p_id=APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq&p_p_lifecycle=0&p_p_state=normal&p_p_mode=view&p_p_col_id=column-3&p_p_col_count=1&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_action=detail&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_id=23&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_idJefe=258&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_menu=info (2015-08-08)
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  • Directory - iib.uam.es
    Directory Service Díaz Guerra González Margarita Category Investigador Científico Position Comisión de Almacén Compras y Equipamiento Laboratory Laboratory of Margarita Díaz Guerra González 2 7 Department Department of Pathophysiology Endocrine and Nervous System Phone Number 34 91 585 4443 Fax 34 91 585 4401 E Mail mdiazguerra Publications View publications New Search Back Navigation Presentation Welcome Location History Biography of Alberto Sols Organization Organization chart Management Administration Institute Board Faculty

    Original URL path: https://www.iib.uam.es/portal/en/personal?p_p_id=APPERSportlet_WAR_APIIBportlet_INSTANCE_vAb1&p_p_lifecycle=0&p_p_col_id=column-3&p_p_col_count=1&_APPERSportlet_WAR_APIIBportlet_INSTANCE_vAb1_idPersona=272&_APPERSportlet_WAR_APIIBportlet_INSTANCE_vAb1_action=detail_person (2015-08-08)
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  • Research Groups - iib.uam.es
    Department of Endocrine and Nervous System Pathophysiology Department of Metabolism and Cell Signaling Department of Experimental Models of Human Disease Scientific Reports Scientific Reports in pdf format Publications Laboratory of Margarita Díaz Guerra González Staff Head of Group Díaz Guerra González Margarita Investigador Contratado Ayuso Dolado Sara Esteban Ortega Gema María Sánchez Tejeda Gonzalo Introduction Staff Research topics Publications Additional Information Navigation Presentation Welcome Location History Biography of Alberto Sols

    Original URL path: https://www.iib.uam.es/portal/en/investigacion/grupos?p_p_id=APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq&p_p_lifecycle=0&p_p_state=normal&p_p_mode=view&p_p_col_id=column-3&p_p_col_count=1&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_action=detail&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_id=84&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_idJefe=272&_APGIportlet_WAR_APIIBportlet_INSTANCE_2Veq_menu=miembros (2015-08-08)
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